Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) designed to mimic a natural polypeptide produced by the pineal gland. It is a potent research tool utilized to investigate aging through two primary mechanisms: the activation of telomerase to elongate telomeres—thereby protecting chromosomes and genomic stability—and the regulation of neuroendocrine function, specifically melatonin production and circadian rhythms.

Preclinical studies validate its potential, demonstrating a 20–30% increase in telomerase activity, a 15–20% reduction in oxidative stress, and a 12–15% lifespan extension in murine models. While these findings offer profound insights into senescence and regenerative biology, Epithalon remains an investigational compound without established human clinical data, limiting its use strictly to laboratory research.

Epithalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide serving as a vital tool for researchers investigating telomerase dynamics and cellular aging. Preclinical data indicates that Epithalon can increase telomerase activity by 20–30%, reduce oxidative stress by 15–20%, and extend lifespan in murine models by 12–15%. These properties make it a precise instrument for studying senescence, regeneration, and neuroendocrine pathways. However, due to a lack of clinical human data, Epithalon remains an investigational compound restricted strictly to laboratory settings.

10 MG Lyophilized Powder in a Vial

Double tested at Janoshik labs (the gold standard of testing in Europe) and at Pure Analytical labs (ISO certified) in California to guarantee 99% purity with zero heavy metals and endotoxins.

Intended Use

This material is sold strictly for the purpose of laboratory research, including but not limited to:

• Cell Signaling Studies: Investigating the interaction between peptides and growth factor pathways (e.g., VEGF, FAK).

• Tissue Culture: Analyzing cellular migration and proliferation in non-clinical models.

• Stability Testing: Assessing peptide degradation rates under various pH and thermal conditions.

Restriction: This product is not a drug, food, or dietary supplement. It has not been approved by the US Food and Drug Administration (FDA) for any clinical application.

Storage & Handling

• Lyophilized State: Store at -20°C (-4°F) or below. Keep vial specifically protected from light to maintain peptide integrity.

• Reconstitution: For best results, reconstitute using Bacteriostatic Water or Sterile Water for Injection (USP) strictly for solution preparation.

• After Reconstitution: The solution should be used immediately for research purposes. If storage is required, maintain at 4°C (39°F) and use within a standard research timeframe (typically 1-2 weeks). Avoid repeated freeze-thaw cycles.